Hollywood star Eric Dane shared a heartfelt Instagram video on September 15, 2025, highlighting his partnership with the I Am ALS organization. Viewers immediately noticed changes in his speech and movements, with some commenting on his “slurred” voice and “twitching” muscles. The video came months after his public ALS diagnosis in April and his absence from the 2025 Emmy Awards, where he was scheduled to celebrate Grey’s Anatomy’s 20th anniversary.

In the video, Dane introduced himself simply: “I’m Eric. An actor, a father, and now a person living with ALS.” He stressed urgency, calling for action against a disease that has remained incurable for over a century. Dane promoted Push for Progress, I Am ALS’s initiative aiming to raise $1 billion in three years to accelerate research, expand treatment access, and update ALS legislation.

He opened up about personal struggles, recounting early symptoms like weakness in his right hand and a recent boating incident where his youngest daughter saved him. Despite these challenges, he praised his wife Rebecca Gayheart and their teenage daughters for their support, noting their bond had strengthened. Dane remains committed to acting, calling it a lifeline that keeps him sharp and motivated. “I don’t think this is the end of my story. I’m fighting as much as I can,” he said.

Now, Dane is more than a Hollywood star; he is a father, advocate, and symbol of resilience. Through his advocacy and courage, he inspires fans and brings attention to ALS, proving that life’s purpose and determination can persist even in the face of life-altering challenges.